Progress in histology and pathogenesis of congenital pulmonary airway malformation / 中华围产医学杂志

Although the molecular mechanism involved in congenital pulmonary airway malformation (CPAM) is not yet clear, many potential genes have been found to be associated with the formation of lung cysts. We review the structural features of tracheobronchial cystic lesions in CPAM, and the regulatory role of fibroblast growth factor, sex-determining region-2 gene and other signaling pathways in CPAM.